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siRNA

Small interfering RNA/silencing RNA (siRNA) is a class of double-stranded, non-coding RNA molecule, 20-25 base pairs in length. As part of the RNA interference pathway, it regulates gene expression by degrading mRNA after transcription, preventing translation.
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1

enQuireBio™ TranslationBlocker Human Notch-1 siRNA

Blocks transcription and translation of Notch-1 from Human.

Accession Number NP_060087
Target Human
Content And Storage Store Lyophilized siRNA duplex at 4°C. Reconsituted product may be stored at -20°C for up to 1 month.
Form Lyophilized
Product Type siRNA
Gene ID (Entrez) 4851
Gene Symbol NOTCH1
Cell Lines Tested Ca Ski Human Carcinoma Cells fro Cervix with Integrated HPV-16 genome.
Synonym AOVD1, TAN1, AOS5, hN1, Neurogenic locus notch homolog protein 1
Shelf Life This product is guaranteed to work for a period of two years when stored at -70°C or colder, and one year when aliquoted and stored at -20°C.
2

enQuireBio™ TranslationBlocker Human Estrogen receptor siRNA

Blocks transcription and translation of Estrogen receptor from Human.

Accession Number NP_000116
Target Human
Content And Storage Store Lyophilized siRNA duplex at 4°C. Reconsituted product may be stored at -20°C for up to 1 month.
Form Lyophilized
Product Type siRNA
Gene ID (Entrez) 2099
Gene Symbol ESR1
Cell Lines Tested MCF7 Human Adenocarcinoma Cells from Breast Cancer.
Synonym ESRA, ESR, NR3A1, ER, ESTRR, Era
Shelf Life This product is guaranteed to work for a period of two years when stored at -70°C or colder, and one year when aliquoted and stored at -20°C.
3

enQuireBio™ TranslationBlocker Human PD-L2 / CD273 siRNA

Blocks transcription and translation of PD-L2 / CD273 from Human.

Accession Number NP_079515
Target Human
Content And Storage Store Lyophilized siRNA duplex at 4°C. Reconsituted product may be stored at -20°C for up to 1 month.
Form Lyophilized
Product Type siRNA
Gene ID (Entrez) 80380
Gene Symbol PDCD1LG2
Cell Lines Tested Hep3b Human Hepatocellular Carinoma Cells, RKO Human Colon Cancer Cells, and Primary Dendritic Cells (DCs) isolated from PBMCs.
Synonym PDL2, CD273, Programmed Cell Death 1 Ligand 2, PDCD1L2, B7-DC, B7DC, PD-1 L2, PD-1 Ligand 2, PDCD1 Ligand 2
Shelf Life This product is guaranteed to work for a period of two years when stored at -70°C or colder, and one year when aliquoted and stored at -20°C.
4

enQuireBio™ TranslationBlocker Human CTLA4 siRNA

Blocks transcription and translation of CTLA4 from Human.

Accession Number NP_005205
Target Human
Content And Storage Store Lyophilized siRNA duplex at 4°C. Reconsituted product may be stored at -20°C for up to 1 month.
Form Lyophilized
Product Type siRNA
Gene ID (Entrez) 1493
Gene Symbol CTLA4
Cell Lines Tested CLL Chronic Lymphoid Leukemia Cells.
Synonym Cytotoxic T-Lymphocyte Associated Protein 4, CTLA-3, CD152, Celiac3, Celiac Disease 3, Cytotoxic T-Lymphocyte-Associated Antigen 4
Shelf Life This product is guaranteed to work for a period of two years when stored at -70°C or colder, and one year when aliquoted and stored at -20°C.
5

enQuireBio™ TranslationBlocker Human TLR7 / CD287 siRNA

Blocks transcription and translation of TLR7 / CD287 from Human.

Accession Number NP_057646
Target Human
Content And Storage Store Lyophilized siRNA duplex at 4°C. Reconsituted product may be stored at -20°C for up to 1 month.
Form Lyophilized
Product Type siRNA
Gene ID (Entrez) 51284
Gene Symbol TLR7
Cell Lines Tested 293T Human Embryonic Kidney Cells with Large T Antigen.
Synonym TLR7-like, TLR7, Toll-like receptor 7, TLR-7
Shelf Life This product is guaranteed to work for a period of two years when stored at -70°C or colder, and one year when aliquoted and stored at -20°C.
6

enQuireBio™ TranslationBlocker Human FADD siRNA

Blocks transcription and translation of FADD from Human.

Accession Number NP_003815
Target Human
Content And Storage Store Lyophilized siRNA duplex at 4°C. Reconsituted product may be stored at -20°C for up to 1 month.
Form Lyophilized
Product Type siRNA
Gene ID (Entrez) 8772
Gene Symbol FADD
Cell Lines Tested 293 Human Embryonic Kidney Cells with NF-kappa B and Flag tagged DR4 constructs.
Synonym Fas Associated Via Death Domain, Fas-Associating Death Domain-Containing Protein, Growth-Inhibiting Gene 3 Protein, Fas (TNFRSF6)-Associated via Death Domain, Protein FADD, MORT1, FAS-Associated Death Domain Protein
Shelf Life This product is guaranteed to work for a period of two years when stored at -70°C or colder, and one year when aliquoted and stored at -20°C.
7

enQuireBio™ TranslationBlocker Human Androgen receptor siRNA

Blocks transcription and translation of Androgen receptor from Human.

Accession Number NP_000035
Target Human
Content And Storage Store Lyophilized siRNA duplex at 4°C. Reconsituted product may be stored at -20°C for up to 1 month.
Form Lyophilized
Product Type siRNA
Gene ID (Entrez) 367
Gene Symbol AR
Cell Lines Tested LNCaP and LNCaP-Rf Androgen Dependent and Independent Metastatic Cells..
Synonym SMAX1, AR8, KD, SBMA, HUMARA, DHTR, HYSP1, TFM, AIS, NR3C4
Shelf Life This product is guaranteed to work for a period of two years when stored at -70°C or colder, and one year when aliquoted and stored at -20°C.
8

enQuireBio™ TranslationBlocker Human ErbB4 / Her4 siRNA

Blocks transcription and translation of ErbB4 / Her4 from Human.

Accession Number NP_005226
Target Human
Content And Storage Store Lyophilized siRNA duplex at 4°C. Reconsituted product may be stored at -20°C for up to 1 month.
Form Lyophilized
Product Type siRNA
Gene ID (Entrez) 2066
Gene Symbol ERBB4
Cell Lines Tested T-47d Human Carcinoma Cells from Breast.
Synonym p180erbB4, HER4, ALS19, Erb-b4, ErbB-4
Shelf Life This product is guaranteed to work for a period of two years when stored at -70°C or colder, and one year when aliquoted and stored at -20°C.
9

enQuireBio™ TranslationBlocker Rat Apoptosis regulator Bcl-2 siRNA

Blocks transcription and translation of Apoptosis regulator Bcl-2 from Rat.

Accession Number NP_058689
Target Rat
Content And Storage Store Lyophilized siRNA duplex at 4°C. Reconsituted product may be stored at -20°C for up to 1 month.
Form Lyophilized
Product Type siRNA
Gene ID (Entrez) 24224
Gene Symbol Bcl2
Cell Lines Tested Pc12 Pheochromocytoma Cells of the Rat Adrenal Gland (Medulla).
Synonym Bcl-2, PPP1R50
Shelf Life This product is guaranteed to work for a period of two years when stored at -70°C or colder, and one year when aliquoted and stored at -20°C.
10

enQuireBio™ TranslationBlocker Human Caspase-2 siRNA

Blocks transcription and translation of Caspase-2 from Human.

Accession Number NP_116765
Target Human
Content And Storage Store Lyophilized siRNA duplex at 4°C. Reconsituted product may be stored at -20°C for up to 1 month.
Form Lyophilized
Product Type siRNA
Gene ID (Entrez) 835
Gene Symbol CASP2
Cell Lines Tested U-2 OS Human Osteosarcoma Epithelial Cells from Bone.
Synonym CASP-2, ICH1, PPP1R57, NEDD-2, NEDD2, CASP2
Shelf Life This product is guaranteed to work for a period of two years when stored at -70°C or colder, and one year when aliquoted and stored at -20°C.
11

enQuireBio™ TranslationBlocker Rat High Affinity Nerve Growth Factor Receptor (TrkA) siRNA

Blocks transcription and translation of High Affinity Nerve Growth Factor Receptor (TrkA) from Rat.

Accession Number NP_067600
Target Rat
Content And Storage Store Lyophilized siRNA duplex at 4°C. Reconsituted product may be stored at -20°C for up to 1 month.
Form Lyophilized
Product Type siRNA
Gene ID (Entrez) 59109
Gene Symbol Ntrk1
Cell Lines Tested Pc12 Rat Pheocromocytoma Cells from the Adrenal Medulla and Rat Primary Neurons.
Synonym TrkA, High Affinity NGFR, NGFR, Trk
Shelf Life This product is guaranteed to work for a period of two years when stored at -70°C or colder, and one year when aliquoted and stored at -20°C.
12

enQuireBio™ TranslationBlocker Rat Estrogen receptor beta siRNA

Blocks transcription and translation of Estrogen receptor beta from Rat.

Accession Number NP_036886
Target Rat
Content And Storage Store Lyophilized siRNA duplex at 4°C. Reconsituted product may be stored at -20°C for up to 1 month.
Form Lyophilized
Product Type siRNA
Gene ID (Entrez) 25149
Gene Symbol Esr2
Cell Lines Tested Rat Primary Osteoblasts.
Synonym ERbeta, Erb2, ER-beta
Shelf Life This product is guaranteed to work for a period of two years when stored at -70°C or colder, and one year when aliquoted and stored at -20°C.
13

enQuireBio™ TranslationBlocker Human Caspase-8 siRNA

Blocks transcription and translation of Caspase-8 from Human.

Accession Number NP_001219
Target Human
Content And Storage Store Lyophilized siRNA duplex at 4°C. Reconsituted product may be stored at -20°C for up to 1 month.
Form Lyophilized
Product Type siRNA
Gene ID (Entrez) 841
Gene Symbol CASP8
Cell Lines Tested 293 Human Embryonic Kidney Cells with NF-kappa B and Flag tagged DR4 constructs.
Synonym CAP4, MCH5, FLICE, MACH, Casp-8, ALPS2B, CASP8
Shelf Life This product is guaranteed to work for a period of two years when stored at -70°C or colder, and one year when aliquoted and stored at -20°C.
14

enQuireBio™ TranslationBlocker Human Alpha-synuclein siRNA

Blocks transcription and translation of Alpha-synuclein from Human.

Accession Number NP_000336
Target Human
Content And Storage Store Lyophilized siRNA duplex at 4°C. Reconsituted product may be stored at -20°C for up to 1 month.
Form Lyophilized
Product Type siRNA
Gene ID (Entrez) 6622
Gene Symbol SNCA
Cell Lines Tested SH-SY5Y.
Synonym PD1, NACP, PARK1, PARK4, SNCA
Shelf Life This product is guaranteed to work for a period of two years when stored at -70°C or colder, and one year when aliquoted and stored at -20°C.
15

enQuireBio™ TranslationBlocker Human Caspase-1 siRNA

Blocks transcription and translation of Caspase-1 from Human.

Accession Number NP_001214
Target Human
Content And Storage Store Lyophilized siRNA duplex at 4°C. Reconsituted product may be stored at -20°C for up to 1 month.
Form Lyophilized
Product Type siRNA
Gene ID (Entrez) 834
Gene Symbol CASP1
Cell Lines Tested Human Primary Keratinocytes.
Synonym Interleukin 1, Beta, Convertase, ICE, Caspase 1
Shelf Life This product is guaranteed to work for a period of two years when stored at -70°C or colder, and one year when aliquoted and stored at -20°C.